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Avy brindle (US brindle)

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Avy brindle, also known as US brindle and tiger brindle, is the viable yellow gene. It produces stripes across the coat in a similar fashion to brindle dogs. The gene arose spontaneously in a lab in 1962.

Unfortunately, like lethal yellow, this gene has links to obesity and brindle mice are often overweight regardless of diet. The likelihood of exhibiting obesity or developing tumours has been linked to the amount of yellow in the coat; the more yellow, the more undesirable effects. Breeding can be slower than with other varieties due to the effects of the obesity.

Brindles come in a variety of colours (not just the typical red). It is dominant to everything on the A locus with the exception of Ay (dominant yellow), although it has been reported that it is co-dominant with tan (at), when no stripes are evident on the mouse's belly. When bred to a self i.e. non-tan, tan offspring are still produced. As with other types of genetically yellow mice, brindles can suffer from sootiness so careful selection for a clear colour is desirable.

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Brindles bred by Nicole Bustamante
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Brindle bred by Nicole Bustamante